The Caenorhabditis elegans Protein FIC-1 Is an AMPylase That Covalently Modifies Heat-Shock 70 Family Proteins, Translation Elongation Factors and Histones

Protein AMPylation by Fic domain-containing proteins (Fic proteins) is an ancient and conserved post-translational modification of mostly unexplored significance. Here we characterize the Caenorhabditis elegans Fic protein FIC-1 in vitro and in vivo. FIC-1 is an AMPylase that localizes to the nuclea...

Descripción completa

Detalles Bibliográficos
Autores principales: Truttmann, Matthias C., Cruz, Victor E., Guo, Xuanzong, Engert, Christoph, Schwartz, Thomas U., Ploegh, Hidde L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854385/
https://www.ncbi.nlm.nih.gov/pubmed/27138431
http://dx.doi.org/10.1371/journal.pgen.1006023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854385/
https://www.ncbi.nlm.nih.gov/pubmed/27138431
http://dx.doi.org/10.1371/journal.pgen.1006023

Ejemplares similares