Knockdown of ApoL1 in Zebrafish Larvae Affects the Glomerular Filtration Barrier and the Expression of Nephrin

APOL1, a secreted high-density lipoprotein, is expressed in different human tissues. Genetic variants of APOL1 are described to be associated with the development of end stage renal diseases in African Americans. In human kidney, APOL1 is mainly expressed in podocytes that are responsible for proper...

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Detalles Bibliográficos
Autores principales: Kotb, Ahmed M., Simon, Ole, Blumenthal, Antje, Vogelgesang, Silke, Dombrowski, Frank, Amann, Kerstin, Zimmermann, Uwe, Endlich, Karlhans, Endlich, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854397/
https://www.ncbi.nlm.nih.gov/pubmed/27138898
http://dx.doi.org/10.1371/journal.pone.0153768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854397/
https://www.ncbi.nlm.nih.gov/pubmed/27138898
http://dx.doi.org/10.1371/journal.pone.0153768

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