Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis

Insulin secretory in pancreatic beta-cells responses to nutrient stimuli and hormonal modulators include multiple messengers and signaling pathways with complex interdependencies. Here we present a computational model that incorporates recent data on glucose metabolism, plasma membrane potential, G-...

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Detalles Bibliográficos
Autores principales: Fridlyand, Leonid E., Philipson, Louis H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854486/
https://www.ncbi.nlm.nih.gov/pubmed/27138453
http://dx.doi.org/10.1371/journal.pone.0152869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854486/
https://www.ncbi.nlm.nih.gov/pubmed/27138453
http://dx.doi.org/10.1371/journal.pone.0152869

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