Killer cell immunoglobulin-like receptor 3DL1 polymorphism defines distinct hierarchies of HLA class I recognition

Natural killer (NK) cells play a key role in immunity, but how HLA class I (HLA-I) and killer cell immunoglobulin-like receptor 3DL1 (KIR3DL1) polymorphism impacts disease outcome remains unclear. KIR3DL1 (*001/*005/*015) tetramers were screened for reactivity against a panel of HLA-I molecules. Thi...

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Detalles Bibliográficos
Autores principales: Saunders, Philippa M., Pymm, Phillip, Pietra, Gabriella, Hughes, Victoria A., Hitchen, Corinne, O’Connor, Geraldine M., Loiacono, Fabrizio, Widjaja, Jacqueline, Price, David A., Falco, Michela, Mingari, Maria Cristina, Moretta, Lorenzo, McVicar, Daniel W., Rossjohn, Jamie, Brooks, Andrew G., Vivian, Julian P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854737/
https://www.ncbi.nlm.nih.gov/pubmed/27045007
http://dx.doi.org/10.1084/jem.20152023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854737/
https://www.ncbi.nlm.nih.gov/pubmed/27045007
http://dx.doi.org/10.1084/jem.20152023

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