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Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production

Circulating levels of fibroblast growth factor 23 (FGF23) are elevated in patients with chronic kidney disease (CKD), but the mechanisms are poorly understood. Here we tested whether inflammation and iron deficiency regulate FGF23. In wild-type mice, acute inflammation induced by single injections o...

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Detalles Bibliográficos
Autores principales: David, Valentin, Martin, Aline, Isakova, Tamara, Spaulding, Christina, Qi, Lixin, Ramirez, Veronica, Zumbrennen-Bullough, Kimberly B., Sun, Chia Chi, Lin, Herbert Y., Babitt, Jodie L., Wolf, Myles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854810/
https://www.ncbi.nlm.nih.gov/pubmed/26535997
http://dx.doi.org/10.1038/ki.2015.290