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Current Approaches Toward Quantitative Mapping of the Interactome

Protein–protein interactions (PPIs) play a key role in many, if not all, cellular processes. Disease is often caused by perturbation of PPIs, as recently indicated by studies of missense mutations. To understand the associations of proteins and to unravel the global picture of PPIs in the cell, diff...

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Detalles Bibliográficos
Autores principales: Buntru, Alexander, Trepte, Philipp, Klockmeier, Konrad, Schnoegl, Sigrid, Wanker, Erich E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854875/
https://www.ncbi.nlm.nih.gov/pubmed/27200083
http://dx.doi.org/10.3389/fgene.2016.00074