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Insights into the Pathology of the α(2)-Na(+)/K(+)-ATPase in Neurological Disorders; Lessons from Animal Models

A functional Na(+)/K(+)-ATPase consists of a catalytic α subunit and a regulatory β subunit. Four α isoforms of the Na(+)/K(+)-ATPase are found in mammals, each with a unique expression pattern and catalytic activity. The α(2) isoform, encoded by the ATP1A2 gene, is primarily found in the central ne...

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Detalles Bibliográficos
Autores principales: Isaksen, Toke J., Lykke-Hartmann, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854887/
https://www.ncbi.nlm.nih.gov/pubmed/27199775
http://dx.doi.org/10.3389/fphys.2016.00161