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Insights into the Pathology of the α(2)-Na(+)/K(+)-ATPase in Neurological Disorders; Lessons from Animal Models
A functional Na(+)/K(+)-ATPase consists of a catalytic α subunit and a regulatory β subunit. Four α isoforms of the Na(+)/K(+)-ATPase are found in mammals, each with a unique expression pattern and catalytic activity. The α(2) isoform, encoded by the ATP1A2 gene, is primarily found in the central ne...
Autores principales: | Isaksen, Toke J., Lykke-Hartmann, Karin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854887/ https://www.ncbi.nlm.nih.gov/pubmed/27199775 http://dx.doi.org/10.3389/fphys.2016.00161 |
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