Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice

We tested the hypothesis that supplementation of nicotinamide mononucleotide (NMN), a key NAD (+) intermediate, increases arterial SIRT1 activity and reverses age‐associated arterial dysfunction and oxidative stress. Old control mice (OC) had impaired carotid artery endothelium‐dependent dilation (E...

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Detalles Bibliográficos
Autores principales: de Picciotto, Natalie E., Gano, Lindsey B., Johnson, Lawrence C., Martens, Christopher R., Sindler, Amy L., Mills, Kathryn F., Imai, Shin‐ichiro, Seals, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854911/
https://www.ncbi.nlm.nih.gov/pubmed/26970090
http://dx.doi.org/10.1111/acel.12461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854911/
https://www.ncbi.nlm.nih.gov/pubmed/26970090
http://dx.doi.org/10.1111/acel.12461

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