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Lack of evidence for GDF11 as a rejuvenator of aged skeletal muscle satellite cells

Recent high‐profile studies report GDF11 to be a key circulating ‘anti‐aging’ factor. However, a screen of extracellular proteins attempting to identify factors with ‘anti‐aging’ phenotypes in aged murine skeletal muscle satellite cells did not identify GDF11 activity. We have been unable to confirm...

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Detalles Bibliográficos
Autores principales: Hinken, Aaron C., Powers, Janine M., Luo, Guizhen, Holt, Jason A., Billin, Andrew N., Russell, Alan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854912/
https://www.ncbi.nlm.nih.gov/pubmed/27139744
http://dx.doi.org/10.1111/acel.12475