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AMPK activation protects cells from oxidative stress‐induced senescence via autophagic flux restoration and intracellular NAD (+) elevation

AMPK activation is beneficial for cellular homeostasis and senescence prevention. However, the molecular events involved in AMPK activation are not well defined. In this study, we addressed the mechanism underlying the protective effect of AMPK on oxidative stress‐induced senescence. The results sho...

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Detalles Bibliográficos
Autores principales: Han, Xiaojuan, Tai, Haoran, Wang, Xiaobo, Wang, Zhe, Zhou, Jiao, Wei, Xiawei, Ding, Yi, Gong, Hui, Mo, Chunfen, Zhang, Jie, Qin, Jianqiong, Ma, Yuanji, Huang, Ning, Xiang, Rong, Xiao, Hengyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854918/
https://www.ncbi.nlm.nih.gov/pubmed/26890602
http://dx.doi.org/10.1111/acel.12446