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Assessing DNA methylation in the developing human intestinal epithelium: potential link to inflammatory bowel disease

DNA methylation is one of the major epigenetic mechanisms implicated in regulating cellular development and cell-type-specific gene expression. Here we performed simultaneous genome-wide DNA methylation and gene expression analysis on purified intestinal epithelial cells derived from human fetal gut...

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Detalles Bibliográficos
Autores principales: Kraiczy, J, Nayak, K, Ross, A, Raine, T, Mak, T N, Gasparetto, M, Cario, E, Rakyan, V, Heuschkel, R, Zilbauer, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854977/
https://www.ncbi.nlm.nih.gov/pubmed/26376367
http://dx.doi.org/10.1038/mi.2015.88