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Assessing DNA methylation in the developing human intestinal epithelium: potential link to inflammatory bowel disease
DNA methylation is one of the major epigenetic mechanisms implicated in regulating cellular development and cell-type-specific gene expression. Here we performed simultaneous genome-wide DNA methylation and gene expression analysis on purified intestinal epithelial cells derived from human fetal gut...
Autores principales: | Kraiczy, J, Nayak, K, Ross, A, Raine, T, Mak, T N, Gasparetto, M, Cario, E, Rakyan, V, Heuschkel, R, Zilbauer, M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854977/ https://www.ncbi.nlm.nih.gov/pubmed/26376367 http://dx.doi.org/10.1038/mi.2015.88 |
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