Caspases uncouple p27(Kip1) from cell cycle regulated degradation and abolish its ability to stimulate cell migration and invasion

In addition to their role in programmed cell death, caspases exert non-lethal functions in diverse developmental processes including cell differentiation or tissue remodeling. Terminal cell cycle exit and differentiation can be promoted by increased level of the CDK inhibitor p27(Kip1). Activated ca...

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Detalles Bibliográficos
Autores principales: Podmirseg, S R, Jäkel, H, Ranches, G D, Kullmann, M K, Sohm, B, Villunger, A, Lindner, H, Hengst, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854979/
https://www.ncbi.nlm.nih.gov/pubmed/26829051
http://dx.doi.org/10.1038/onc.2015.524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854979/
https://www.ncbi.nlm.nih.gov/pubmed/26829051
http://dx.doi.org/10.1038/onc.2015.524

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