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Liquid Chromatography-Mass Spectrometry-Based In Vitro Metabolic Profiling Reveals Altered Enzyme Expressions in Eicosanoid Metabolism

BACKGROUND: Eicosanoids are metabolites of arachidonic acid that are rapidly biosynthesized and degraded during inflammation, and their metabolic changes reveal altered enzyme expression following drug treatment. We developed an eicosanoid profiling method and evaluated their changes on drug treatme...

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Detalles Bibliográficos
Autores principales: Lee, Su Hyeon, Kim, Eung Ju, Lee, Dong-Hyoung, Lee, Won-Yong, Chung, Bong Chul, Seo, Hong Seog, Choi, Man Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Laboratory Medicine 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855054/
https://www.ncbi.nlm.nih.gov/pubmed/27139607
http://dx.doi.org/10.3343/alm.2016.36.4.342