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Biodegradable interstitial release polymer loading a novel small molecule targeting Axl receptor tyrosine kinase and reducing brain tumour migration and invasion

Glioblastoma multiforme (GBM) is the most common and aggressive brain tumour. The neoplasms are difficult to resect entirely because of their highly infiltration property and leading to the tumour edge is unclear. Gliadel wafer has been used as an intracerebral drug delivery system to eliminate the...

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Detalles Bibliográficos
Autores principales: Yen, S-Y, Chen, S-R, Hsieh, J, Li, Y-S, Chuang, S-E, Chuang, H-M, Huang, M-H, Lin, S-Z, Harn, H-J, Chiou, T-W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855077/
https://www.ncbi.nlm.nih.gov/pubmed/26257061
http://dx.doi.org/10.1038/onc.2015.277