The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP(3) pathway

The ability of radial glial progenitors (RGPs) to generate cortical neurons is determined by local extracellular factors and signaling pathways intrinsic to RGPs. Here we find that GPR157, an orphan G protein-coupled receptor, localizes to RGPs’ primary cilia exposed to the cerebrospinal fluid (CSF)...

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Detalles Bibliográficos
Autores principales: Takeo, Yutaka, Kurabayashi, Nobuhiro, Nguyen, Minh Dang, Sanada, Kamon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855140/
https://www.ncbi.nlm.nih.gov/pubmed/27142930
http://dx.doi.org/10.1038/srep25180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855140/
https://www.ncbi.nlm.nih.gov/pubmed/27142930
http://dx.doi.org/10.1038/srep25180

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