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The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP(3) pathway
The ability of radial glial progenitors (RGPs) to generate cortical neurons is determined by local extracellular factors and signaling pathways intrinsic to RGPs. Here we find that GPR157, an orphan G protein-coupled receptor, localizes to RGPs’ primary cilia exposed to the cerebrospinal fluid (CSF)...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855140/ https://www.ncbi.nlm.nih.gov/pubmed/27142930 http://dx.doi.org/10.1038/srep25180 |