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Microgravity Induction of TRAIL Expression in Preosteoclast Cells Enhances Osteoclast Differentiation

Evidence indicates that astronauts experience significant bone loss in space. We previously showed that simulated microgravity (μXg) using the NASA developed rotary cell culture system (RCCS) enhanced bone resorbing osteoclast (OCL) differentiation. However, the mechanism by which μXg increases OCL...

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Detalles Bibliográficos
Autores principales: Sambandam, Yuvaraj, Baird, Kelsey L., Stroebel, Maxwell, Kowal, Emily, Balasubramanian, Sundaravadivel, Reddy, Sakamuri V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855152/
https://www.ncbi.nlm.nih.gov/pubmed/27142480
http://dx.doi.org/10.1038/srep25143