Matrix stiffness promotes cartilage endplate chondrocyte calcification in disc degeneration via miR-20a targeting ANKH expression

The mechanical environment is crucial for intervertebral disc degeneration (IDD). However, the mechanisms underlying the regulation of cartilage endplate (CEP) calcification by altered matrix stiffness remain unclear. In this study, we found that matrix stiffness of CEP was positively correlated wit...

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Detalles Bibliográficos
Autores principales: Liu, Ming-Han, Sun, Chao, Yao, Yuan, Fan, Xin, Liu, Huan, Cui, You-Hong, Bian, Xiu-Wu, Huang, Bo, Zhou, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855171/
https://www.ncbi.nlm.nih.gov/pubmed/27142968
http://dx.doi.org/10.1038/srep25401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855171/
https://www.ncbi.nlm.nih.gov/pubmed/27142968
http://dx.doi.org/10.1038/srep25401

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