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Hypothalamus proteomics from mouse models with obesity and anorexia reveals therapeutic targets of appetite regulation

OBJECTIVE: This study examined the proteomic profile of the hypothalamus in mice exposed to a high-fat diet (HFD) or with the anorexia of acute illness. This comparison could provide insight on the effects of these two opposite states of energy balance on appetite regulation. METHODS: Four to six-we...

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Detalles Bibliográficos
Autores principales: Manousopoulou, A, Koutmani, Y, Karaliota, S, Woelk, C H, Manolakos, E S, Karalis, K, Garbis, S D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855256/
https://www.ncbi.nlm.nih.gov/pubmed/27110685
http://dx.doi.org/10.1038/nutd.2016.10