Proteasome inhibitors, including curcumin, improve pancreatic β-cell function and insulin sensitivity in diabetic mice

BACKGROUND: Type 2 diabetes stems from obesity-associated insulin resistance, and in the genetically susceptible, concomitant pancreatic β-cell failure can occur, which further exacerbates hyperglycemia. Recent work by our group and others has shown that the natural polyphenol curcumin attenuates th...

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Detalles Bibliográficos
Autores principales: Weisberg, S, Leibel, R, Tortoriello, D V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855258/
https://www.ncbi.nlm.nih.gov/pubmed/27110686
http://dx.doi.org/10.1038/nutd.2016.13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855258/
https://www.ncbi.nlm.nih.gov/pubmed/27110686
http://dx.doi.org/10.1038/nutd.2016.13

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