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Gut macrophage phenotype is dependent on the tumor microenvironment in colorectal cancer

In contrast to many cancers, a high infiltration of macrophages in colorectal cancer (CRC) has been associated with improved prognosis for patients. Cytokines and other stimuli from the tumor microenvironment affect monocyte to macrophage maturation and subsequent phenotype and function. Heterogeneo...

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Detalles Bibliográficos
Autores principales: Norton, Samuel E, Dunn, Elliott T J, McCall, John L, Munro, Fran, Kemp, Roslyn A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855270/
https://www.ncbi.nlm.nih.gov/pubmed/27195119
http://dx.doi.org/10.1038/cti.2016.21