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Co-culture with neonatal cardiomyocytes enhances the proliferation of iPSC-derived cardiomyocytes via FAK/JNK signaling

BACKGROUND: We previously reported that the pluripotent stem cells can differentiate into cardiomyocytes (CMs) by co-culture with neonatal CMs (NCMs) in vitro. However, the involving mechanism is not clear. METHODS: Mouse induced pluripotent stem cells (iPSCs) were cultured in hanging drops to form...

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Detalles Bibliográficos
Autores principales: Ou, Dongbo, Wang, Qi, Huang, Yanjin, Zeng, Di, Wei, Ting, Ding, Lu, Li, Xiaoli, Zheng, Qiangsun, Jin, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855360/
https://www.ncbi.nlm.nih.gov/pubmed/27141946
http://dx.doi.org/10.1186/s12861-016-0112-2