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Hierarchical classification strategy for Phenotype extraction from epidermal growth factor receptor endocytosis screening

BACKGROUND: Endocytosis is regarded as a mechanism of attenuating the epidermal growth factor receptor (EGFR) signaling and of receptor degradation. There is increasing evidence becoming available showing that breast cancer progression is associated with a defect in EGFR endocytosis. In order to fin...

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Detalles Bibliográficos
Autores principales: Cao, Lu, Graauw, Marjo de, Yan, Kuan, Winkel, Leah, Verbeek, Fons J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855371/
https://www.ncbi.nlm.nih.gov/pubmed/27142862
http://dx.doi.org/10.1186/s12859-016-1053-2