Perturbation of the two-component signal transduction system, BprRS, results in attenuated virulence and motility defects in Burkholderia pseudomallei

BACKGROUND: Burkholderia pseudomallei is the causative agent of melioidosis, a severe invasive disease of humans and animals. Initial screening of a B. pseudomallei signature-tagged mutagenesis library identified an attenuated mutant with a transposon insertion in a gene encoding the sensor componen...

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Detalles Bibliográficos
Autores principales: Lazar Adler, Natalie R., Allwood, Elizabeth M., Deveson Lucas, Deanna, Harrison, Paul, Watts, Stephen, Dimitropoulos, Alexandra, Treerat, Puthayalai, Alwis, Priyangi, Devenish, Rodney J., Prescott, Mark, Govan, Brenda, Adler, Ben, Harper, Marina, Boyce, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855414/
https://www.ncbi.nlm.nih.gov/pubmed/27147217
http://dx.doi.org/10.1186/s12864-016-2668-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855414/
https://www.ncbi.nlm.nih.gov/pubmed/27147217
http://dx.doi.org/10.1186/s12864-016-2668-4

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