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Perturbation of the two-component signal transduction system, BprRS, results in attenuated virulence and motility defects in Burkholderia pseudomallei
BACKGROUND: Burkholderia pseudomallei is the causative agent of melioidosis, a severe invasive disease of humans and animals. Initial screening of a B. pseudomallei signature-tagged mutagenesis library identified an attenuated mutant with a transposon insertion in a gene encoding the sensor componen...
Autores principales: | Lazar Adler, Natalie R., Allwood, Elizabeth M., Deveson Lucas, Deanna, Harrison, Paul, Watts, Stephen, Dimitropoulos, Alexandra, Treerat, Puthayalai, Alwis, Priyangi, Devenish, Rodney J., Prescott, Mark, Govan, Brenda, Adler, Ben, Harper, Marina, Boyce, John D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855414/ https://www.ncbi.nlm.nih.gov/pubmed/27147217 http://dx.doi.org/10.1186/s12864-016-2668-4 |
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