Cargando…

Interactions between inflammatory mediators and corticosteroids regulate transcription of genes within the Kynurenine Pathway in the mouse hippocampus

BACKGROUND: Increased tryptophan metabolism towards the production of kynurenine via indoleamine/tryptophan-2,3-dioxygenases (DOs: Ido1, Ido2, and Tdo2) is strongly associated with the prevalence of major depressive disorder in patients and the induction of depression-like behaviors in animal models...

Descripción completa

Detalles Bibliográficos
Autores principales:	Brooks, Alexandra K., Lawson, Marcus A., Smith, Robin A., Janda, Tiffany M., Kelley, Keith W., McCusker, Robert H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855471/ https://www.ncbi.nlm.nih.gov/pubmed/27142940 http://dx.doi.org/10.1186/s12974-016-0563-1

Ejemplares similares

Immunomodulatory Factors Galectin-9 and Interferon-Gamma Synergize to Induce Expression of Rate-Limiting Enzymes of the Kynurenine Pathway in the Mouse Hippocampus
por: Brooks, Alexandra K., et al.
Publicado: (2016)

Glial and tissue-specific regulation of Kynurenine Pathway dioxygenases by acute stress of mice
por: Dostal, Carlos R., et al.
Publicado: (2017)

Interleukin-1 beta converting enzyme is necessary for development of depression-like behavior following intracerebroventricular administration of lipopolysaccharide to mice
por: Lawson, Marcus A, et al.
Publicado: (2013)

Insulin-like growth factor-I peptides act centrally to decrease depression-like behavior of mice treated intraperitoneally with lipopolysaccharide
por: Park, Sook-Eun, et al.
Publicado: (2011)

Intracerebroventricular administration of lipopolysaccharide induces indoleamine-2,3-dioxygenase-dependent depression-like behaviors
por: Lawson, Marcus A, et al.
Publicado: (2013)

Endogenous Synthesis of Corticosteroids in the Hippocampus
por: Higo, Shimpei, et al.
Publicado: (2011)

Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge
por: Parrott, Jennifer M., et al.
Publicado: (2016)

Central administration of insulin-like growth factor-I decreases depressive-like behavior and brain cytokine expression in mice
por: Park, Sook-Eun, et al.
Publicado: (2011)

CSF Concentrations of Brain Tryptophan and Kynurenines during Immune Stimulation with IFN-alpha: Relationship to CNS Immune Responses and Depression
por: Raison, Charles L., et al.
Publicado: (2009)

Corticosteroid Regulation of Synaptic Plasticity in the Hippocampus
por: Maggio, Nicola, et al.
Publicado: (2010)

Schistosoma mansoni alter transcription of immunomodulatory gene products following in vivo praziquantel exposure
por: McCusker, Paul, et al.
Publicado: (2021)

Prenatal inhibition of the kynurenine pathway leads to structural changes in the hippocampus of adult rat offspring
por: Khalil, Omari S, et al.
Publicado: (2014)

Differential Transcriptome Networks between IDO1-Knockout and Wild-Type Mice in Brain Microglia and Macrophages
por: Gonzalez-Pena, Dianelys, et al.
Publicado: (2016)

The quest for quarks
por: McCusker, Brian
Publicado: (1983)

Cellular self-organization: generating order from the abyss
por: McCusker, Derek
Publicado: (2020)

Neurotoxic kynurenine metabolism is increased in the dorsal hippocampus and drives distinct depressive behaviors during inflammation
por: Parrott, J M, et al.
Publicado: (2016)

High Transverse Momenta in Collisions at Cosmic Ray Energies
por: McCusker, C B A
Publicado: (1978)

The Kynurenine Pathway and Kynurenine 3-Monooxygenase Inhibitors
por: Hughes, Tamera D., et al.
Publicado: (2022)

The Rts1 Regulatory Subunit of Protein Phosphatase 2A Is Required for Control of G1 Cyclin Transcription and Nutrient Modulation of Cell Size
por: Artiles, Karen, et al.
Publicado: (2009)

Can touch imprint cytology replace fine needle aspiration within current clinical practice?
por: Kinkaid, H, et al.
Publicado: (2010)

Is a Motor Criterion Essential for the Diagnosis of Clinical Huntington Disease?
por: Loy, Clement T, et al.
Publicado: (2013)

Huntington Disease: The Complexities of Making and Disclosing a Clinical Diagnosis After Premanifest Genetic Testing
por: McCusker, Elizabeth A., et al.
Publicado: (2017)

Neural control of growth and size in the axolotl limb regenerate
por: Wells, Kaylee M, et al.
Publicado: (2021)

Trimethylation of Histone 3 lysine 27 (H3K27me3) ChIP-PCR and transcriptional expression data of Ef1-alpha, cyp26A, HoxC10, HoxD10 and HoxD11 in the Xenopus XTC cell line
por: Vieira, Warren, et al.
Publicado: (2017)

A post-transcriptional regulatory landscape of aging in the female mouse hippocampus
por: Winsky-Sommerer, Raphaelle, et al.
Publicado: (2023)

Primary immunodeficiency
por: McCusker, Christine, et al.
Publicado: (2011)

The Many Facets of Unawareness in Huntington Disease
por: McCusker, Elizabeth, et al.
Publicado: (2014)

Transcriptional and morphological profiling of parvalbumin interneuron subpopulations in the mouse hippocampus
por: Que, Lin, et al.
Publicado: (2021)

Regenerative Models for the Integration and Regeneration of Head Skeletal Tissues
por: Vieira, Warren A., et al.
Publicado: (2018)

Modulation of Enzyme Activity in the Kynurenine Pathway by Kynurenine Monooxygenase Inhibition
por: Phillips, Robert S., et al.
Publicado: (2019)

Are Kynurenines Accomplices or Principal Villains in Dementia? Maintenance of Kynurenine Metabolism
por: Tanaka, Masaru, et al.
Publicado: (2020)

Integration failure of regenerated limb tissue is associated with incongruencies in positional information in the Mexican axolotl
por: Vieira, Warren A., et al.
Publicado: (2023)

Differential Consolidation and Pattern Reverberations within Episodic Cell Assemblies in the Mouse Hippocampus
por: Oşan, Remus, et al.
Publicado: (2011)

Rubella screening programme--preliminary results in Northern Ireland.
por: McClelland, W. M., et al.
Publicado: (1983)

Editorial: Alternative Therapeutics against MDR Bacteria – “Fighting the Epidemic of Antibiotic Resistance”
por: Martins, Marta, et al.
Publicado: (2016)

Anti-schistosomal action of the calcium channel agonist FPL-64176
por: McCusker, Paul, et al.
Publicado: (2019)

Hypericum Perforatum Decreased Hippocampus TNF-α and Corticosterone Levels with No Effect on Kynurenine/Tryptophan Ratio in Bilateral Ovariectomized Rats
por: El-Bakly, Wesam M, et al.
Publicado: (2014)

What do we know about Late Onset Huntington’s Disease?
por: Chaganti, Sai S., et al.
Publicado: (2017)

An orexigenic subnetwork within the human hippocampus
por: Barbosa, Daniel A. N., et al.
Publicado: (2023)

Microglia Transcriptome Changes in a Model of Depressive Behavior after Immune Challenge
por: Gonzalez-Pena, Dianelys, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_vlnb6avlj3mmu7g5hfthk0q3j8