Crystal structure of a substrate-engaged SecY protein-translocation channel

Hydrophobic signal sequences target secretory polypeptides to a protein-conducting channel formed by a heterotrimeric membrane protein complex, the prokaryotic SecY or eukaryotic Sec61 complex. How signal sequences are recognized is poorly understood, particularly because they are diverse in sequenc...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Long, Park, Eunyong, Ling, JingJing, Ingram, Jessica, Ploegh, Hidde, Rapoport, Tom A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855518/
https://www.ncbi.nlm.nih.gov/pubmed/26950603
http://dx.doi.org/10.1038/nature17163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855518/
https://www.ncbi.nlm.nih.gov/pubmed/26950603
http://dx.doi.org/10.1038/nature17163

Ejemplares similares