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Crystal structure of a substrate-engaged SecY protein-translocation channel

Hydrophobic signal sequences target secretory polypeptides to a protein-conducting channel formed by a heterotrimeric membrane protein complex, the prokaryotic SecY or eukaryotic Sec61 complex. How signal sequences are recognized is poorly understood, particularly because they are diverse in sequenc...

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Detalles Bibliográficos
Autores principales:	Li, Long, Park, Eunyong, Ling, JingJing, Ingram, Jessica, Ploegh, Hidde, Rapoport, Tom A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855518/ https://www.ncbi.nlm.nih.gov/pubmed/26950603 http://dx.doi.org/10.1038/nature17163

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