An exact algorithm for finding cancer driver somatic genome alterations: the weighted mutually exclusive maximum set cover problem

BACKGROUND: The mutual exclusivity of somatic genome alterations (SGAs), such as somatic mutations and copy number alterations, is an important observation of tumors and is widely used to search for cancer signaling pathways or SGAs related to tumor development. However, one problem with current met...

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Detalles Bibliográficos
Autores principales: Lu, Songjian, Mandava, Gunasheil, Yan, Gaibo, Lu, Xinghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855522/
https://www.ncbi.nlm.nih.gov/pubmed/27148394
http://dx.doi.org/10.1186/s13015-016-0073-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855522/
https://www.ncbi.nlm.nih.gov/pubmed/27148394
http://dx.doi.org/10.1186/s13015-016-0073-9

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