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An exact algorithm for finding cancer driver somatic genome alterations: the weighted mutually exclusive maximum set cover problem
BACKGROUND: The mutual exclusivity of somatic genome alterations (SGAs), such as somatic mutations and copy number alterations, is an important observation of tumors and is widely used to search for cancer signaling pathways or SGAs related to tumor development. However, one problem with current met...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855522/ https://www.ncbi.nlm.nih.gov/pubmed/27148394 http://dx.doi.org/10.1186/s13015-016-0073-9 |