Structure‐activity relationship of the peptide binding‐motif mediating the BRCA2:RAD51 protein–protein interaction

RAD51 is a recombinase involved in the homologous recombination of double‐strand breaks in DNA. RAD51 forms oligomers by binding to another molecule of RAD51 via an ‘FxxA’ motif, and the same recognition sequence is similarly utilised to bind BRCA2. We have tabulated the effects of mutation of this...

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Detalles Bibliográficos
Autores principales: Scott, Duncan E., Marsh, May, Blundell, Tom L., Abell, Chris, Hyvönen, Marko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Letters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855620/
https://www.ncbi.nlm.nih.gov/pubmed/26992456
http://dx.doi.org/10.1002/1873-3468.12139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855620/
https://www.ncbi.nlm.nih.gov/pubmed/26992456
http://dx.doi.org/10.1002/1873-3468.12139

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