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Searching for cognitive enhancement in the Morris water maze: better and worse performance in D‐amino acid oxidase knockout (Dao (−/−)) mice

A common strategy when searching for cognitive‐enhancing drugs has been to target the N‐methyl‐d‐aspartate receptor (NMDAR), given its putative role in synaptic plasticity and learning. Evidence in favour of this approach has come primarily from studies with rodents using behavioural assays like the...

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Detalles Bibliográficos
Autores principales: Pritchett, David, Taylor, Amy M, Barkus, Christopher, Engle, Sandra J, Brandon, Nicholas J, Sharp, Trevor, Foster, Russell G, Harrison, Paul J, Peirson, Stuart N, Bannerman, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855640/
https://www.ncbi.nlm.nih.gov/pubmed/26833794
http://dx.doi.org/10.1111/ejn.13192