GSK-3β-induced Tau pathology drives hippocampal neuronal cell death in Huntington's disease: involvement of astrocyte–neuron interactions

Glycogen synthase kinase-3β (GSK-3β) has emerged as a critical factor in several pathways involved in hippocampal neuronal maintenance and function. In Huntington's disease (HD), there are early hippocampal deficits both in patients and transgenic mouse models, which prompted us to investigate...

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Detalles Bibliográficos
Autores principales: L'Episcopo, F, Drouin-Ouellet, J, Tirolo, C, Pulvirenti, A, Giugno, R, Testa, N, Caniglia, S, Serapide, M F, Cisbani, G, Barker, R A, Cicchetti, F, Marchetti, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855649/
https://www.ncbi.nlm.nih.gov/pubmed/27124580
http://dx.doi.org/10.1038/cddis.2016.104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855649/
https://www.ncbi.nlm.nih.gov/pubmed/27124580
http://dx.doi.org/10.1038/cddis.2016.104

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