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A cardiac mitochondrial cAMP signaling pathway regulates calcium accumulation, permeability transition and cell death
Although cardiac cytosolic cyclic 3′,5′-adenosine monophosphate (cAMP) regulates multiple processes, such as beating, contractility, metabolism and apoptosis, little is known yet on the role of this second messenger within cardiac mitochondria. Using cellular and subcellular approaches, we demonstra...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855650/ https://www.ncbi.nlm.nih.gov/pubmed/27100892 http://dx.doi.org/10.1038/cddis.2016.106 |