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A cardiac mitochondrial cAMP signaling pathway regulates calcium accumulation, permeability transition and cell death

Although cardiac cytosolic cyclic 3′,5′-adenosine monophosphate (cAMP) regulates multiple processes, such as beating, contractility, metabolism and apoptosis, little is known yet on the role of this second messenger within cardiac mitochondria. Using cellular and subcellular approaches, we demonstra...

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Detalles Bibliográficos
Autores principales: Wang, Z, Liu, D, Varin, A, Nicolas, V, Courilleau, D, Mateo, P, Caubere, C, Rouet, P, Gomez, A-M, Vandecasteele, G, Fischmeister, R, Brenner, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855650/
https://www.ncbi.nlm.nih.gov/pubmed/27100892
http://dx.doi.org/10.1038/cddis.2016.106