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Eiger-induced cell death relies on Rac1-dependent endocytosis

Signaling via tumor necrosis factor receptor (TNFR) superfamily members regulates cellular life and death decisions. A subset of mammalian TNFR proteins, most notably the p75 neurotrophin receptor (p75NTR), induces cell death through a pathway that requires activation of c-Jun N-terminal kinases (JN...

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Detalles Bibliográficos
Autores principales: Ruan, W, Srinivasan, A, Lin, S, Kara, k-I, Barker, P A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855659/
https://www.ncbi.nlm.nih.gov/pubmed/27054336
http://dx.doi.org/10.1038/cddis.2016.80