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A novel differentiation pathway from CD4(+) T cells to CD4(−) T cells for maintaining immune system homeostasis

CD4(+) T lymphocytes are key players in the adaptive immune system and can differentiate into a variety of effector and regulatory T cells. Here, we provide evidence that a novel differentiation pathway of CD4(+) T cells shifts the balance from a destructive T-cell response to one that favors regula...

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Detalles Bibliográficos
Autores principales: Zhao, X, Sun, G, Sun, X, Tian, D, Liu, K, Liu, T, Cong, M, Xu, H, Li, X, Shi, W, Tian, Y, Yao, J, Guo, H, Zhang, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855662/
https://www.ncbi.nlm.nih.gov/pubmed/27077809
http://dx.doi.org/10.1038/cddis.2016.83