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MicroRNA-682-mediated downregulation of PTEN in intestinal epithelial cells ameliorates intestinal ischemia–reperfusion injury

Intestinal ischemia–reperfusion (I/R) injury causes inflammation and tissue damage and contributes to high morbidity and mortality, but the underlying mechanism remains elusive and effective therapies are still lacking. We report here a critical role of the microRNA 682 (miR-682) as a key regulator...

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Detalles Bibliográficos
Autores principales: Liu, Z, Jiang, J, Yang, Q, Xiong, Y, Zou, D, Yang, C, Xu, J, Zhan, H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855663/
https://www.ncbi.nlm.nih.gov/pubmed/27124584
http://dx.doi.org/10.1038/cddis.2016.84