Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence

Activation of quiescent hepatic stellate cells (HSCs) is the major event in hepatic fibrogenesis, along with enhancement of cell proliferation and overproduction of extracellular matrix. Although inhibition of cell proliferation and induction of apoptosis are potential strategies to block the activa...

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Detalles Bibliográficos
Autores principales: Jin, H, Lian, N, Zhang, F, Chen, L, Chen, Q, Lu, C, Bian, M, Shao, J, Wu, L, Zheng, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855671/
https://www.ncbi.nlm.nih.gov/pubmed/27077805
http://dx.doi.org/10.1038/cddis.2016.92

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855671/
https://www.ncbi.nlm.nih.gov/pubmed/27077805
http://dx.doi.org/10.1038/cddis.2016.92

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