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Tumor suppression in mice lacking GABARAP, an Atg8/LC3 family member implicated in autophagy, is associated with alterations in cytokine secretion and cell death

GABARAP belongs to an evolutionary highly conserved gene family that has a fundamental role in autophagy. There is ample evidence for a crosstalk between autophagy and apoptosis as well as the immune response. However, the molecular details for these interactions are not fully characterized. Here, w...

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Detalles Bibliográficos
Autores principales: Salah, F S, Ebbinghaus, M, Muley, V Y, Zhou, Z, Al-Saadi, K R D, Pacyna-Gengelbach, M, O'Sullivan, G A, Betz, H, König, R, Wang, Z-Q, Bräuer, R, Petersen, I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855672/
https://www.ncbi.nlm.nih.gov/pubmed/27124579
http://dx.doi.org/10.1038/cddis.2016.93