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TAK1 regulates Paneth cell integrity partly through blocking necroptosis
Paneth cells reside at the base of crypts of the small intestine and secrete antimicrobial factors to control gut microbiota. Paneth cell loss is observed in the chronically inflamed intestine, which is often associated with increased reactive oxygen species (ROS). However, the relationship between...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855677/ https://www.ncbi.nlm.nih.gov/pubmed/27077812 http://dx.doi.org/10.1038/cddis.2016.98 |