Forced Degradation Studies of Ivabradine and In Silico Toxicology Predictions for Its New Designated Impurities

All activities should aim to eliminate genotoxic impurities and/or protect the API against degradation. There is a necessity to monitor impurities from all classification groups, hence ivabradine forced degradation studies were performed. Ivabradine was proved to be quite durable active substance, b...

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Detalles Bibliográficos
Autores principales: Pikul, Piotr, Jamrógiewicz, Marzena, Nowakowska, Joanna, Hewelt-Belka, Weronika, Ciura, Krzesimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855699/
https://www.ncbi.nlm.nih.gov/pubmed/27199759
http://dx.doi.org/10.3389/fphar.2016.00117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855699/
https://www.ncbi.nlm.nih.gov/pubmed/27199759
http://dx.doi.org/10.3389/fphar.2016.00117

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