TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells

BACKGROUND: Abnormal DNA methylation/demethylation is recognized as a hallmark of cancer. TET (ten-eleven translocation) family members are novel DNA demethylation related proteins that dysregulate in multiple malignances. However, their effects on ovarian cancer remain to be elucidated. METHODS: Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Ye, Zhongxue, Li, Jie, Han, Xi, Hou, Huilian, Chen, He, Zheng, Xia, Lu, Jiaojiao, Wang, Lijie, Chen, Wei, Li, Xu, Zhao, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855705/
https://www.ncbi.nlm.nih.gov/pubmed/27141829
http://dx.doi.org/10.1186/s13046-016-0350-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855705/
https://www.ncbi.nlm.nih.gov/pubmed/27141829
http://dx.doi.org/10.1186/s13046-016-0350-y

Ejemplares similares