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TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells
BACKGROUND: Abnormal DNA methylation/demethylation is recognized as a hallmark of cancer. TET (ten-eleven translocation) family members are novel DNA demethylation related proteins that dysregulate in multiple malignances. However, their effects on ovarian cancer remain to be elucidated. METHODS: Th...
Autores principales: | Ye, Zhongxue, Li, Jie, Han, Xi, Hou, Huilian, Chen, He, Zheng, Xia, Lu, Jiaojiao, Wang, Lijie, Chen, Wei, Li, Xu, Zhao, Le |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855705/ https://www.ncbi.nlm.nih.gov/pubmed/27141829 http://dx.doi.org/10.1186/s13046-016-0350-y |
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