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Characterization of novel Bovine Leukemia Virus (BLV) antisense transcripts by deep sequencing reveals constitutive expression in tumors and transcriptional interaction with viral microRNAs

BACKGROUND: Bovine Leukemia Virus (BLV) is a deltaretrovirus closely related to the Human T cell leukemia virus-1 (HTLV-1). Cattle are the natural host of BLV where it integrates into B-cells, producing a lifelong infection. Most infected animals remain asymptomatic but following a protracted latenc...

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Detalles Bibliográficos
Autores principales: Durkin, Keith, Rosewick, Nicolas, Artesi, Maria, Hahaut, Vincent, Griebel, Philip, Arsic, Natasa, Burny, Arsène, Georges, Michel, Van den Broeke, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855707/
https://www.ncbi.nlm.nih.gov/pubmed/27141823
http://dx.doi.org/10.1186/s12977-016-0267-8