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Utilization of HIV-1 envelope V3 to identify X4- and R5-specific Tat and LTR sequence signatures
BACKGROUND: HIV-1 entry is a receptor-mediated process directed by the interaction of the viral envelope with the host cell CD4 molecule and one of two co-receptors, CCR5 or CXCR4. The amino acid sequence of the third variable (V3) loop of the HIV-1 envelope is highly predictive of co-receptor utili...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855882/ https://www.ncbi.nlm.nih.gov/pubmed/27143130 http://dx.doi.org/10.1186/s12977-016-0266-9 |