Utilization of HIV-1 envelope V3 to identify X4- and R5-specific Tat and LTR sequence signatures

BACKGROUND: HIV-1 entry is a receptor-mediated process directed by the interaction of the viral envelope with the host cell CD4 molecule and one of two co-receptors, CCR5 or CXCR4. The amino acid sequence of the third variable (V3) loop of the HIV-1 envelope is highly predictive of co-receptor utili...

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Detalles Bibliográficos
Autores principales: Antell, Gregory C., Dampier, Will, Aiamkitsumrit, Benjamas, Nonnemacher, Michael R., Jacobson, Jeffrey M., Pirrone, Vanessa, Zhong, Wen, Kercher, Katherine, Passic, Shendra, Williams, Jean W., Schwartz, Gregory, Hershberg, Uri, Krebs, Fred C., Wigdahl, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855882/
https://www.ncbi.nlm.nih.gov/pubmed/27143130
http://dx.doi.org/10.1186/s12977-016-0266-9

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