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Single-cell profiling of human megakaryocyte-erythroid progenitors identifies distinct megakaryocyte and erythroid differentiation pathways

BACKGROUND: Recent advances in single-cell techniques have provided the opportunity to finely dissect cellular heterogeneity within populations previously defined by “bulk” assays and to uncover rare cell types. In human hematopoiesis, megakaryocytes and erythroid cells differentiate from a shared p...

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Detalles Bibliográficos
Autores principales: Psaila, Bethan, Barkas, Nikolaos, Iskander, Deena, Roy, Anindita, Anderson, Stacie, Ashley, Neil, Caputo, Valentina S., Lichtenberg, Jens, Loaiza, Sandra, Bodine, David M., Karadimitris, Anastasios, Mead, Adam J., Roberts, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855892/
https://www.ncbi.nlm.nih.gov/pubmed/27142433
http://dx.doi.org/10.1186/s13059-016-0939-7