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Sjögren’s syndrome-associated microRNAs in CD14(+) monocytes unveils targeted TGFβ signaling

BACKGROUND: Sjögren’s syndrome (SjS) monocytes have a pro-inflammatory phenotype, which may influence SjS pathogenesis. MicroRNAs (miRNAs) are small endogenously expressed molecules that can inhibit protein expression of their targeted genes and have important functions in regulating cell signaling...

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Detalles Bibliográficos
Autores principales: Williams, Adrienne E. G., Choi, Kevin, Chan, Annie L., Lee, Yun Jong, Reeves, Westley H., Bubb, Michael R., Stewart, Carol M., Cha, Seunghee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4855899/
https://www.ncbi.nlm.nih.gov/pubmed/27142093
http://dx.doi.org/10.1186/s13075-016-0987-0